What drugs are used for paediatric anaesthesia?

On 20170713, I brought Little Prince for a paediatric anaesthesia pre-surgery review and asked about drugs that are used for his surgical procedure.

Anesthesia medicine may affect brain development in children, especially those under 3 – 4 years old, according to different studies in USA (including a FDA warning) and Singapore.

More alarming, child deaths from both local and general anesthesia have been reported.

According to Stanford, “medications currently used for sedation have the same toxicities as general anesthetic agents.

According to a study in Minnesota, children receiving 2/> anesthetics, have an increased risk for learning disability.

However, in children exposed to a single anesthetic, no statistically significant association between receiving general anesthesia and poor academic performance, according to studies performed in Denmark, Netherlands, and by Mayo.

Below are the drugs that the pediatric anaesthetist told us:

***
Propofol
Administration: IV
Effects: can cause dizziness/drowsiness
Concerning effects (need to inform doctors asap): weak/shallow breathing, hives, swelling of face, lips, tongue, or throat.

***
Sevoflurane
Administration: inhalation
Effects: agitation, dizziness, drowsiness, vomiting
Concerning effects: neurotoxicity, do not use it if a patient has or has a history of severely high body temperature.

***
Atracurium
Functions: neuromuscular blockers
Administration: IV
Concerning effects: bronchospasm (hence difficulty in breathing)

***
Fentanyl
Functions: pain relief
Administration: solution/injectable
Effects: sweating, fever, respiratory depression, nausea, vomiting, shallow/slow breathing if overdose

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